The Inn at Southbridge occupies a contemporary, vine-draped building one block from the center of St. Helena, one of Napa Valley’s most charming towns. The inn shares its neighborhood with the Merryvale Winery, Health Spa Napa Valley, and several acclaimed restaurants. Guests are primarily couples who appreciate the quiet setting, handsomely appointed rooms, and proximity to dozens of wineries.

English country-estate living awaits guests at this Tudor-style hotel set on eight acres of landscaped grounds in St. Helena, with flower gardens and redwood arbors. Leisure travelers, including many wine lovers, marvel at the lobby with its 20-foot ceilings, exposed wood beams, stained-glass windows, and ornately carved staircase.

This Napa riverfront hotel offers individuals, couples, groups, and corporate travelers superior service and a peaceful retreat while visiting Napa Valley. Guests often gather to exchange winery recommendations in the lobby, which has a fireplace, wine-tasting bar, and dramatic examples of regional landscape art. The outdoor terrace faces onto the river and a nature preserve on the opposite bank.

What to expect: This modern condominium resort is located at the southern end of Napa Valley. Couples, families, and groups of friends appreciate the spacious condos and the proximity to hundreds of wineries in both the Napa and Sonoma valleys. San Francisco is just 42 miles away—perfect for a day trip. Guests enjoy access to the underground spa, lap pool, restaurant, tasting room, and other facilities at the adjacent Meritage Resort, where they also check in.

Amenity highlights: A large, inviting sundeck surrounds the Vino Bello's outdoor pool, spa tub, wading pool, and children's water feature. Gas barbecue grills and picnic tables are adjacent.

Guests can indulge in a treatment at the underground Spa Terra, located at the adjacent resort (a 5-minute walk). The spa, built into a hillside, offers Tuscan-inspired therapies in a hushed setting of vaulted ceilings, water walls, and glittering mosaics.

Insider tip: The Artesa Winery, 7.5 miles from the Vino Bello, is on many must-visit lists. Innovative architecture, dazzling modern sculptures and paintings, waterfalls, and reflecting pools set the scene for award-winning red and white wines. Guests can sample Pinot Noirs, Cabernet Sauvignons, and other selections (fee) in the dramatically designed tasting room or take them out to the terrace, with spectacular views of vine-covered hills.